U.S.News综合大学排名是全美最具权威影响力最大的排名。此排名里的大学为综合性研究型大学，提供学士、硕士和博士课程，专业设置齐全。
| Rank | School name | City | Tuition | Total medical school enrollment |
|---|---|---|---|---|
| #1 | University of Pennsylvania (Perelman) | Philadelphia, PA | $48,738 (full-time) | 665 |
| #2 | Harvard University | Boston, MA | $52,100 (full-time) | 708 |
| #3 | University of Cincinnati | Cincinnati, OH | $29,096 (in-state, full-time); $47,004 (out-of-state, full-time) | 667 |
| #4 | Johns Hopkins University | Baltimore, MD | $45,750 (full-time) | 484 |
| #5 | University of Washington | Seattle, WA | $29,958 (in-state, full-time); $58,947 (out-of-state, full-time) | 918 |
| #6 | University of Colorado—Denver | Aurora, CO | $33,663 (in-state, full-time); $59,618 (out-of-state, full-time) | 646 |
| #7 | University of Pittsburgh | Pittsburgh, PA | $46,962 (in-state, full-time); $48,138 (out-of-state, full-time) | 602 |
| #8 | University of California—San Francisco | San Francisco, CA | $32,106 (in-state, full-time); $44,351 (out-of-state, full-time) | 632 |
| #9 | Baylor College of Medicine | Houston, TX | $19,650 (full-time) | 747 |
| #10 | Stanford University | Stanford, CA | $48,999 (full-time) | 468 |
| #10 | Washington University in St. Louis | St. Louis, MO | $54,050 (full-time) | 485 |
